If an apple a day keeps the doctor away, an Appletini a day should keep you not just healthy, but happy. No tongue depressor, this trendy cocktail (it's also known as the Original Sin, as in Eve going for the apple) tastes quite a bit like an apple Jolly Rancher. And Panzano's version of the Appletini does that homegrown candy proud: It's a smooth, sippable treat. Containing equal portions of Vox Vodka and DeKuyper Sour Apple Pucker, the bright-lime-colored drink ($6.50) is served chilled and straight-up. The appletini is part of a warm-weather cocktail roster recently introduced at Panzano, the northern-Italian eatery tucked into the swank Hotel Monaco in the heart of the downtown banking district. (The restaurant has a new spring menu, too.) But the bar works well year-round: All dark wood and big windows, it's an oasis for both working (several power booths are available) and playing professionals, as well as tourists and local loft dwellers. The smells of warm bread and garlic wafting from the kitchen next door are almost as reviving as the Appletini. Almost. Here's to your health.