It's big, it's bold, and for nearly fifty years, this family owned establishment has been both a neighborhood staple and a regional destination for anyone and everyone, from the guys looking for the cheapest fifth available or a 24-pack of party beers, to party planners who need five cases of reasonably priced cabernet, to wine, spirits and beer geeks seeking the latest hot bottle or offering from the newest Colorado craft brewers or distillers. In 2008, Argonaut Wine & Liquor decided to expand dramatically, but it stayed in the same gritty location, helping to revitalize the block around it while adding to its already massive selection. The store also hosts frequent charity drives and off-site tastings that benefit local nonprofits. And that is something to toast.