Not only can artsy types Tran and Josh Wills turn out a mighty fine screenprint, but they can sure run a business. The Fabric Lab, an eclectic shop featuring locally designed clothing, accessories and handbags, is going strong at 3105 East Colfax, has sparked a couture renaissance along this once-stagnant strip. There's the Big Hairy Monster hair salon; the Willses' new cupcake and design emporium, the Shoppe; Jen Garner's Neopolitan gallery; and the urban vinyl store Plastic Chapel. And just up the street, at 2907 East Colfax, is Newspeak, a tattoo, apparel and art-supply business dreamed up by the folks at Indy Ink clothing store and Brave New World tattoo parlor; next door, Bad Kitty Salon proffers killer hairstyles and local art. Recently, the proprietors of these like-minded businesses have started throwing art-based block parties on the second Saturday of each month. Here comes the neighborhood.