Comedy and alcohol have always shared an enduring but volatile symbiosis, but few shows court boozy overindulgence like Designated Drunkard: A Comedy Drinking Game. A local franchise of a showcase format that originated in New Orleans --where dignified day-drinking is a resident's birthright-- Designated Drunkard turns the foibles, obsessions and tics of local and traveling standups into prompts for the audience to take a drink. Co-hosts Caitie Hannan and Westword's own Byron Graham not only produce and emcee the show, but one of them will be sitting onstage in the titular role of "Designated Drunkard," leading the audience in shot challenges and rotating roles each month for the sake of their livers. Presented in partnership with Sexpot Comedy, September's show features local mirth merchants Georgia Rae, Patrick Scott and Zac Maas along with the well-traveled Reid Clark and Chicago's Basil Faraj opening for Denver Comedy Champion Nathan Lund. Visit the Sexpot Comedy calendar to learn more and get your tickets, $5, from Nightout.