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From its start 25 years ago in the Evergreen garage of James Jackson, a real-estate developer turned philanthropist, Project C.U.R.E. has grown into the world's largest distributor of donated medical supplies and equipment, distributing roughly $50 million of relief every year. Today the organization is run by Douglas Jackson and operates out of a 60,000-square-foot warehouse in Centennial. But C.U.R.E. doesn't just send supplies around the globe; it also sends volunteers, who quickly recognize that the cure for many of the world's ills starts right here in Colorado.

Readers' Choice: New Era Colorado

These two polar bears are bonkers for each other. Before Lee came to the Denver Zoo last year, Cranbeary was a ten-year-old widow whose romance with Frosty was short-lived, since the bear had succumbed to liver cancer a month after Cranbeary arrived in Denver. But Lee, a handsome twelve-year-old from Detroit, seems to have filled that gap nicely. The two bears spend their days frolicking in the habitat's pool, Dirty Dancing style, and then shamelessly spooning in public.

Only twelve 2011 National Arts and Humanities Youth Program Awards were given out last year, each with a $10,000 grant, and Denver's PlatteForum won one of them. Feted for its artist-student mentoring work, the gallery/workshop on Platte Street was handed its award by Michelle Obama in November. "I always saw the world as gray until PlatteForum opened up my vision," said student participant Salvador Flores-Martinez, who joined PlatteForum director Judy Anderson and education director Meagan Terry on the trip to Washington, D.C., to pick up the honor. We're all seeing more clearly, thanks to PlatteForum.

Though it won't officially open until late April 2012, it's not too early to rate the urbane History Colorado Center a rousing architectural success. The 200,000-square-foot building was designed to house all the functions of the Colorado Historical Society — including offices, event facilities and a replacement for the thirty-year-old museum, whose former spot a block away is now part of the still-under-construction state justice center. The price tag on this stunner was over $110 million, but it got a jump start in 2010 with the issuance of Build America Bonds, part of the federal stimulus program to fund "shovel-ready" public projects. The sleek neo-modernist building, with its canted volumes and dramatic cantilevered cornice, is clad in dull limestone and detailed with shiny aluminum and even a touch of rusted steel. It's the crowning achievement of its designer, Tryba Architects (headed by David Tryba) — and, along with the nearby Wellington Webb building, the firm's second great contribution to the greater Civic Center.

Parker was once a small, rural town — but after the last few building booms, it's been completely subsumed by suburban sprawl that's spread developer housing, strip malls and gas stations across the area. But there's still a remnant of an old downtown on Main Street, and on a nearby ridge that rises above Sulphur Gulch, the town council, using a little over $20 million in existing funds, decided to build the Parker Arts, Culture and Events center, known as PACE. The facility, which opened last fall, includes a theater, an auditorium, a media lab, an art gallery and a dance studio. Done by Denver's Semple Brown Design, the smart-looking structure is made up of interlocking horizontal forms in concrete and brick that have been beautifully detailed. The pierced-metal wall is out of this world — and definitely outside the bland box that holds most of the rest of Parker's architecture.

As the mother of three and a practicing physician at Denver Health's Westside Family Health Center for two decades, Irene Aguilar had her hands full. Still, she found the time to run for Senate District 32 in the Colorado Legislature, and, since winning that election in 2010, has kept a dizzying pace both in the Capitol and out among her constituents. She's a whiz on health-care issues and has held numerous town meetings on that issue, among other topics. And every Monday, she invites a crew of University of Denver law students to her office to study the pros and cons of a potential piece of legislation. If people are tired of politics as usual, Aguilar could be just the tonic.

Readers' Choice: Michael Hancock

For fifty years, the Northwoods Inn served meat to the masses. It was a Colorado institution where it was okay to throw peanut shells on the floor and a ragtime piano player entertained diners while they gnawed steaks and savored the special seasoned cottage cheese. But the restaurant closed abruptly last year, replaced by a business that's another kind of meat market altogether. This address is now the new home of the Scarlet Ranch swingers' club, which left its old home on Broadway for the 'burbs . Here's to another fifty years of T-bones!

The Denver Department of Parks and Recreation had seven acres of underutilized, wilderness-like land at the edge of northwest Denver: the former Camp Rollandet, which the city had purchased from the Campfire Girls in 2005. The local branch of Outward Bound, a national organization that got its start in Marble fifty years ago, had long been headquartered in stuffy urban office spaces and was looking for a new home. The deal was a natural, and late last year, Outward Bound leased the Camp Rollandet site with the blessing of the Denver City Council. Kudos all around: A beautiful slice of nature is a terrible thing to waste.

Unlike many of those other city-ranking, hit-seeking Internet lists (which have cumulatively described Denver as "the manliest, drunkest city"), last November's accolade from the Brookings Institution had some real science behind it. Demographer William Frey, a senior fellow with the Metropolitan Policy Program, parsed the numbers from the U.S. Census Bureau's American Community Survey and determined that from 2008 through 2010, even as the hopes for a quick comeback from the recession faded, young adults between the ages of 25 and 34 were high on Denver...and proved it by coming here in record numbers. Although Denver ranked a mediocre twelfth in Frey's last survey, which covered 2005 through 2007, since then it had pulled ahead of such previous hotspots as Phoenix and Atlanta, adding a chart-topping 10,429 new, young residents, to rank as the country's top cool city. "What we see from the migration data," Frey said, is that "Colorado and Denver are probably a part of the country that will survive and possibly prosper when the economy comes back." Cool!

Best Place to Symbolize Denver for the Rest of the World

Wynkoop Brewing Company

Wynkoop Brewing

Since the first wave of gold-hunters washed up on the banks of Cherry Creek, Denver has always attracted pioneers. In fact, Governor John Hickenlooper made this state's entrepreneurial spirit the focus of his State of the State speech this January. And no one better exemplifies that spirit than Hickenlooper, an East Coast-educated geologist who moved out to Colorado in the early '80s, was laid off in the middle of that decade's oil-and-gas bust, and joined with other adventurers to start Denver's first brewpub, the Wynkoop Brewing Company, which opened in 1988. Since then, of course, craft beer has become a major growth industry in Colorado...and Hickenlooper himself wound up using the bar as a launching pad for a political career that took him first to City Hall, then to the State Capitol. Although Hickenlooper is no longer involved with the Wynkoop, it remains a great place to get a taste of Denver's history, whether you're drinking its brews inside the renovated, Victorian-era warehouse or sitting on the Wynkoop-side patio, watching the sun set over the mountains...and the Union Station project, which will transform that piece of history into a futuristic, multi-modal transportation hub by 2014.

Readers' Choice: Red Rocks Amphitheatre

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