Mezcal mecca Palenque originally opened in 2018 as a second location of Adelitas but took the Palenque name after former co-owners Silvia Andaya (who still runs the original on Broadway) and Brian Rossi cut ties in 2020. Two years into its new iteration, there's no better place south of the city to learn about — and sip plenty of — a well-curated selection of agave spirits and cocktails paired with eats like tacos, ceviche, mole, enchiladas and more. Bonus: the rooftop patio.