But considerably more people in Denver and Colorado are dying each year from other opioids — including methadone and prescription drugs such as OxyContin and fentanyl — than perish as a result of heroin use. And while the upticks in fatalities isn't as sharp as the ones related to heroin, they're still substantial. In Colorado, deaths from opioids other than heroin are up 128 percent from fifteen years ago, while Denver's fatality total has risen by 372 percent.
As in our previous piece, the statistics shared here were provided by the Colorado Department of Public Health and Environment under the auspices of Kirk Bol, manager of the agency's registries and vital-statistics branch, as well as chair of its internal review board. He notes that the category "Any opioid analgesic" is broken into three main subcategories: "Natural and semi-synthetic opioid analgesics," which includes drugs with the "oxy" prefix, as well as hydrocodone, codeine and the like; "Synthetic opioid analgesic," comprising fully synthetic drugs such as fentanyl; and methadone.
In 2001, the first year for which the CDPHE provided data, eleven people in Denver and 118 people statewide died from opioid analgesics in these three categories combined. Compare that with 2016, for which provisional numbers are available; final stats should be out later in the springtime. The current opioid-death numbers for last year are 269 for Colorado and 52 in Denver.
Each of these totals is higher than the 2016 provisional figures for heroin: 197 for Colorado, 31 for Denver.
Bol points out that "there's been some leveling off in our opioid deaths over the past couple of years." The Colorado opioid-analgesic-death numbers peaked in 2014, with 338 fatalities — meaning that the 2016 sum is 69 deaths lower. That same year, 65 people died from opioid-analgesic-related causes in Denver, thirteen more than the 2016 provisional number.
The decline over the past three years may be the result of what Bol characterizes as a crackdown on opioid painkiller abuse. Some theorize that these efforts may have pushed more people to heroin, resulting in the disturbing casualty figures for that narcotic enumerated above.
Also troubling is the data for methadone. The substance is often used as a replacement for heroin in addiction treatment, but it can be deadly in its own right. Last year, provisionally, 52 people in Colorado and ten in Denver died with methadone in their system.
The increasing abuse of fentanyl and other synthetic opioid analgesics stands out, too. In 2001, nineteen deaths from such drugs took place in Colorado, with none in Denver. During 2016, the deaths of ten Denverites and 55 Coloradans have been linked to these substances.
Figures for the past fifteen years are on view below. You'll notice that the sum of the three subcategories sometimes exceeds the combined any-opioid-analgesic number. The reason, Bol explains, is that some people had more than one of the drugs in their system when they died.

Methadone is used to help heroin users kick the habit, but it, too, can have fatal consequences.
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Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 118
Denver — 11
Natural and semi-synthetic opioid analgesic
Colorado — 91
Denver — 6
Methadone
Colorado — 19
Denver — 4
Synthetic opioid analgesic
Colorado — 19
Denver — 0
2002
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 119
Denver — 15
Natural and semi-synthetic opioid analgesic
Colorado — 70
Denver — 8
Methadone
Colorado — 27
Denver — 5
Synthetic opioid analgesic
Colorado — 28
Denver — 0
2003
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 118
Denver — 22
Natural and semi-synthetic opioid analgesic
Colorado — 72
Denver — 9
Methadone
Colorado — 30
Denver — 10
Synthetic opioid analgesic
Colorado — 22
Denver — 4
2004
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 138
Denver — 16
Natural and semi-synthetic opioid analgesic
Colorado — 80
Denver — 8
Methadone
Colorado — 40
Denver — 8
Synthetic opioid analgesic
Colorado — 22
Denver — 0
2005
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 179
Denver — 25
Natural and semi-synthetic opioid analgesic
Colorado — 104
Denver — 11
Methadone
Colorado — 54
Denver — 13
Synthetic opioid analgesic
Colorado — 35
Denver — 4
2006
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 201
Denver — 32
Natural and semi-synthetic opioid analgesic
Colorado — 123
Denver — 17
Methadone
Colorado — 61
Denver — 15
Synthetic opioid analgesic
Colorado — 26
Denver — 3
2007
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 269
Denver — 66
Natural and semi-synthetic opioid analgesic
Colorado — 181
Denver — 54
Methadone
Colorado — 58
Denver — 11
Synthetic opioid analgesic
Colorado — 44
Denver — 7
2008
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 246
Denver — 63
Natural and semi-synthetic opioid analgesic
Colorado — 175
Denver — 47
Methadone
Colorado — 48
Denver — 15
Synthetic opioid analgesic
Colorado — 38
Denver — 7
2009
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 279
Denver — 73
Natural and semi-synthetic opioid analgesic
Colorado — 171
Denver — 49
Methadone
Colorado — 56
Denver — 13
Synthetic opioid analgesic
Colorado — 67
Denver — 16
2010
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 227
Denver — 40
Natural and semi-synthetic opioid analgesic
Colorado — 136
Denver — 26
Methadone
Colorado — 48
Denver — 10
Synthetic opioid analgesic
Colorado — 44
Denver — 7
2011
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 304
Denver — 59
Natural and semi-synthetic opioid analgesic
Colorado — 196
Denver — 39
Methadone
Colorado — 60
Denver — 15
Synthetic opioid analgesic
Colorado — 75
Denver — 11
2012
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 295
Denver — 43
Natural and semi-synthetic opioid analgesic
Colorado — 223
Denver — 32
Methadone
Colorado — 43
Denver — 7
Synthetic opioid analgesic
Colorado — 51
Denver — 6
2013
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 295
Denver — 46
Natural and semi-synthetic opioid analgesic
Colorado — 218
Denver — 37
Methadone
Colorado — 41
Denver — 6
Synthetic opioid analgesic
Colorado — 67
Denver — 12
2014
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 338
Denver — 65
Natural and semi-synthetic opioid analgesic
Colorado — 249
Denver — 54
Methadone
Colorado — 48
Denver — 9
Synthetic opioid analgesic
Colorado — 78
Denver — 10
2015
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 329
Denver — 52
Natural and semi-synthetic opioid analgesic
Colorado — 259
Denver — 41
Methadone
Colorado — 34
Denver — 8
Synthetic opioid analgesic
Colorado — 65
Denver — 9
2016 (provisional)
Any opioid analgesic (natural, synthetic, methadone, et. al.)
Colorado — 269
Denver — 52
Natural and semi-synthetic opioid analgesic
Colorado — 188
Denver — 42
Methadone
Colorado — 51
Denver — 10
Synthetic opioid analgesic
Colorado — 55
Denver — 10