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Dear Panda: Unless you're applying for some ultra-classified or important job, not really. The most common drug test used by employers is a five-panel urinalysis test, which flags cocaine, opiates, amphetamines (meth), phencyclidine (PCP) and, for some reason, THC (cannabis). There are eight-, ten- and twelve-panel tests as well, but they're too expensive for most workplace drug tests, and even the vast majority of twelve-panel tests don't check for psilocybin (the psychoactive compound in magic mushrooms).

Flickr/Charles de Mille-Isles
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